Endocrine Abstracts

Introduction: A positive correlation between serum thyrotropin concentrations (TSH) and body mass index (BMI) has been demonstrated. Some studies not shown this, in euthyroid subjects, or observed only if thyroid autoimmunity (TA) is present or in non-smokers (NS). Leptin (Lp) could be the major link between BMI and TSH.Design: To analyze the relationship between TSH, free thyroxine (FT4), Lp, TA (peroxidase and/or thyroglobulin antibodies) an...

Introduction: Leptin seems to be a major link between obesity and thyroid dysfunction.Design: To analyze the relationship between thyrotropin (TSH) and leptin (LP) plasma concentrations and body mass index (BMI), in 785 subjects (448 women) of 41.27±9.72 years and BMI 28.91±9.8 (18.04–93.98 kg/m2), without diagnosed thyroid disease or pregnancy, concentrations of TSH, free thyroxine (FT4), LP, glycemia and insulinemia...

Introduction: The clinical significance of subclinical thyroid diseases is debated.Design: To assess the relationship between undiagnosed subclinical hypothyroidism (USH), health indicators (HI) and cardiovascular risk factors (CVRF), this cross-sectional study was conducted in 1100 adults representatives of non-institutionalized Catalan population (44.5% men; mean age: 44.8±15.2 years) in Catalonia (Spain); 40 USH (18 men) and 1060 euthyroid (474 m...

Introduction: Ghrelin gene products ghrelin and obestatin have apparent opposite orexigenic and anorexigenic effects, although this latter has not been firmly demonstrated for obestatin in humans. So far, no information has been reported in relation to its potential association to metabolic syndrome (MS).Objective: To study obestatin concentrations in relation to nutritional parameters and eating behavior in old women.Methods: One ...